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Iowa State University

Iowa State University
Picture of Max F.Rothschild
Max F. Rothschild
C.F. Curtiss Distinguished Professor in Agriculture
M.E. Ensminger International Chair
Director, Center for Integrated Animal Genomics
US Pig Genome Coordinator
Iowa State University
2255 Kildee Hall
Ames, IA 50011-3150
Phone: 515-294-6202
Fax:     515-294-2401
Email: mfrothsc@iastate.edu

Education
Doctor of Philosophy, Cornell University: 1978 (Animal Breeding, minors in Genetics and Statistics)
Master of Science, University of Wisconsin-Madison: 1975 (Animal Science)
Bachelor of Science, University of California-Davis: 1974 (Animal Science)

Awards
2009: Distinguished Service Award, American Society of Agricultural Editors
2008: International Animal Agriculture Award, American Society of Animal Science
2007: M.E.Ensminger Endowed Chair in Animal Agriculture
2007: Fellow, American Society of Animal Science
2007: Order of the Knoll Faculty Award, ISU Foundation
2007: International Service Award, Iowa State University
2006: Faculty Award for Diversity Enhancement (College of Agriculture)
2005: Charles Stanislaw Memorial Distinguished Service Award (National Swine Improvement Federation)
2003: Excellence in International Agriculture Award (College of Agriculture)
2003: Mission Award for Research (Gamma Sigma Delta)
2003: Outstanding Achievement in Research Award (ISU Foundation)
2002: Inventor of the Year (Iowa Intellectual Property Law Association)
2002: R and D 100 Award (MC4R)
1999: R&D 100 Award (ESR)
1998: Fellow, American Association for the Advancement of Science
1997: USDA Honor Team Award
1995: American Society of Animal Science Animal Breeding and Genetics Award

Instruction
Dr. Rothschild is a guest lecturer for several undergraduate and graduate courses

Research
Dr. Rothschild's areas of research are gene mapping; identification of genes controlling growth; reproduction and immunogenetics of swine; and new statistical methods to evaluate animals, gene identification in dogs and shrimp.

Professional Affiliations
Phi Sigma Pi Honorary Society
Gamma Sigma Delta Honorary Agriculture Society
American Society of Animal Science
International Society of Animal Genetics
American Dairy Science Association
American Association for Advancement of Science,
International Mammalian Genome Society

Selected Publications
Complete List of Publications

Wilke, V.L., Conzemius, M.G., Kinghorn, B.P., Macrossan, P.E., Weiguo, C., M. F. Rothschild. 2006. Predicting the inheritance of rupture of the cranial cruciate ligament in the Newfoundland dog. J Am Vet Med Assoc. 228: 61-64.

Vincent, A.L., B. J. Thacker, P. G. Halbur, M. F. Rothschild, and E. L. Thacker. 2006. An investigation of susceptibility to porcine reproductive and respiratory syndrome virus between two genetically diverse commercial lines of pigs. J. Animal Science 84:49-57.

Grapes, L., M. Z. Firat, J. C. M. Dekkers, M. F. Rothschild, R. L. Fernando. 2006. Optimal haplotype structure for linkage disequilibrium-based fine mapping of quantitative trait loci. Genetics 172-1955-1965.

Opriessnig T., M. Fenaux, P. Thomas, M. J. Hoogland, M. F. Rothschild, X. J. Meng, and P. G. Halbur. 2006. Evidence of breed-dependent differences in susceptibility to porcine circovirus type 2-associated disease and lesions. Veterinary Pathology 43:281-293.

Maneeruttanarungroj, C., S. Pongsomboon, S. Wuthisuthimethavee, S. Klinbunga, K.J. Wilson, J. Swan, Y.Li, V. Whan, K-H. Chu, C.P. Li, J. Tong, K. Glenn, M. F. Rothschild, D. Jerry and A. Tassanakajon. 2006. Development of polymorphic expressed sequence tag-derived microsatellites for the extension of the genetic linkage map of the black tiger shrimp (Penaeus monodon). Anim Genetics 37:263-368.

Yu, M., B. Geiger, N. Deeb, and M. F. Rothschild. 2006. Liver X receptor alpha and beta genes have the potential role on loin lean and fat content in pigs. J. Anim. Breed. Genet. 123:81-88

Mote, B.E. and M. F. Rothschild. 2006. SNP detection and linkage mapping of pig genes involved in growth. Animal Genetics 37:295-296

Ramos, A. J. Helm, J. Sherwood, D. Rocha and M. F. Rothschild. 2006. Mapping of 21 genetic markers to a QTL region for meat quality on pig chromosome 17. Animal Genetics. 37:296-297

Grapes, L. S. Rudd, R. L. Fernando,K . Meg, D. Rocha and M. F. Rothschild 2006. Prospecting for pig SNPs in the human genome: have we struck gold? J. Animal. Breed Genet. 123:145-151

Motodiev, S., B. Mote and M. F. Rothschild. 2006. Mapping of the porcine CCS and CCR7 genes Bulgarian Journal of Agricultural Science 12:153-157.

Hittmeier, L.J., L. Grapes, R.L. Lensing, M. F. Rothschild, C.H. Stahl. 2006. Genetic Background Influences Response to Dietary Phosphorous Restriction. J Nutritional Biochemistry17:385-395.

Yu, M. Y. Cheung and M. F. Rothschild. 2006. SNP analysis of moulting genes in Peneaus monodon and Liteopeneaus vannemai shrimp. An Breed Archives 4:411-412

Van Cleave, P. K.L. Glenn, B.E. Mote and M. F. Rothschild. 2006. Mapping of CARD to pig chromosome 18. An Breed Archives 5:517-518.

Mote, B. and M. F. Rothschild. 2006. Cracking the Genomic Piggy Bank: Identifying Secrets of the Pig Genome. Genome Dynamics 2:86-96.

Grapes, L. and M. F. Rothschild. 2006. Investigation of a QTL region for loin eye area and fatness on pig chromosome 1. Mammalian Genome 17: 657-668.

Nguyen, V.C., K.L. Glenn, B.E. Mote and M. F. Rothschild. 2006. Mapping of ACE to pig chromosome 12. An Breed Archives 6:617-618.

Kollers, S., B. Mote, M. F. Rothschild, G.S. Plastow and and D. Rocha. 2006. Single nucleotide polymorphism identification, linkage and radiation hybrid mapping of the porcine pituitary adenylate cyclase-activating polypeptide type I receptor gene to chromosome 18. J. An Breed Genet 123:414-418

Rothschild, M.F., P. S. Van Cleave, K. L. Glenn, L. P. Carlstrom and N. M. Ellinwood. 2006. Association of MITF with white spotting in Beagle crosses and Newfoundland dogs. Animal Genetics 37:606-607.

Ott, G., R. Roche, H. Looft, L. Thoelking, P.W. Knap, M. F. Rothschild, G.S. Plastow and E. Kalm. 2006. Associations of DNA markers with meat quality traits in pigs with emphasis on drip loss. Meat Sci 75:185-195.

Glenn, K, L., A. M. Ramos, and M. F. Rothschild. 2007. Analysis of FMO genes and off flavor in pork. J. An Breed and Genetics 124:35-38

Qu, A., M. F. Rothschild and C.H. Stahl. 2007. Effect of dietary phosphorus and its interaction with genetic background on global gene expression in porcine muscle. J. An Breeding and Genetics 124:214-224

Guimaraes, S., M. F. Rothschild, C. H Stahl, and S. M. Lonergan. 2007. SNP discovery, expression and association analysis for the SDHD gene in pigs. J. An Breed and Genetics 124:246-253

Hart, E.A., M. Caccamo, J.L. Harrow, S. Humphray, J. G.R. Gilbert, S. Trevanion, T. Hubbard, J. Rogers and M. F. Rothschild. 2007. Lessons learned from the initial sequencing of the pig genome: comparative analysis of an 8 MB region of pig chromosome 17. Genome Biology 8: R168.

Huang, T.H., B. Fan, M. F. Rothschild, Z.-L. Hu, K. Li, S.-H. Zhao. 2007. MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans. BMC Bioinformatics 8:341.

Ramos, A.M. T. V. Serenius, K. J. Stalder, and M. F. Rothschild. 2007. Phenotypic correlations among processing quality traits of fresh and dry-cured hams. Meat Sci 77:182-189.

Yu, M., B. Geiger, N. Deeb and M. F. Rothschild. 2007. Investigation of TXNIP (Thioredoxin-Interacting Protein) and TRX (Thioredoxin) Genes for Growth-Related Traits in Pigs. Mammal Genome 18:197-209

Guimaraes, S.E.F., C. H. Stahl, S. M. Lonergan, B. Geiger, and M. F. Rothschild. 2007. Myostatin promoter analysis and expression pattern in pigs. Livestock Prod Sci 112:143-150

Jiang, Z., S. Pappu and M. F. Rothschild. 2007. Hitting the jackpot twice: identifying and patenting gene tests related to muscle lipid accumulation for meat quality in animals and Type 2 diabetes/obesity in humans. Recent patents on DNA &Gene Sequences 1:100-111.

Jiang, Z. and M. F. Rothschild. 2007. Swine genome science comes of age. Int. J. Biol. Sci. 3: 129-131.

Rothschild, M.F., Z.H. Hu and Z. Jiang. 2007. Advances in QTL mapping in pigs. Int. J. Biol. Sci. 3: 192-197.

Do, K. T., Y. Ha, B. E. Mote, M. F. Rothschild, B. H. Choi, S. S. Lee, T. H. Kim, B. W. Cho, K. S. Kim. 2008 Investigation of single nucleotide polymorphisms in porcine chromosome 2 quantitative trait loci for meat quality traits. Asian-Aust. J. Anim. Sci. 21: 155-160

Li, X., Z-L. Hu, K. Do, S. Moon, Y. Ha, H. Kim, B-H. Choi, M. F. Rothschild, J. M. Reecy, and K-S. Kim. 2008. Development and characterization of an in silico coding gene SNP map in pigs. Anim. Genet. 39: 446-450.

Yu, M., M. F. Rothschild, J. Yang, S.H. Zhao, K. Li. 2008. Linkage mapping of five genes on SSC12 in a Berkshire × Yorkshire cross. Archive of Animal Breeding. (in press)

Fan, B., K.L. Glenn, B. Geiger, A. Mileham, and M. F. Rothschild. 2009. Investigation of QTL regions on chromosome 17 for genes associated with meat color in the pig. J. Anim. Breed. Genet. 125: 240-247

Ramos, A. M., K. L. Glenn, T. V. Serenius, K. J. Stalder, and M. F. Rothschild. 2008. Genetic markers for the production of US Country Hams. Meat Sci 125:1-10.

Rothschild, M.F. and G.S. Plastow. 2008. Impact of genomics in animal agriculture and opportunities for animal health. Trends in Biotechnology. 26:21-25.

Li, X.P., K. T. Do, J.-J. Kim, J. Huang, S. H. Zhao, Y. Lee, M. F. Rothschild, C. K. Lee and K. S. Kim. 2008. Molecular characteristics of the porcine DLK1 and MEG3 genes Animal Genetics 39:189-192

Onteru, S.K., B. Fan, M. F. Rothschild. 2008. SNP detection and comparative linkage mapping of 66 bone-related genes in the pig. Cytogenet. Genome Res. 122:122-131.

Onteru, S.K., B. Mote, T. Serenius, M. Nikkilae, K. J. Stalder, M. F. Rothschild. 2008. SNP discovery in genes affecting leg health traits in pigs. Pinard M-H, Gay C, Pastoret P-P, Dodet B (Eds): Animal Genomics for Animal Health. Dev Biol (Basel). Basel, Karger, 132: 337-342

Du, Z.-Q., B. Fan, X. Zhao, R. Amoako, and M. F. Rothschild. 2008. Association analyses between type 2 Diabetes genes and obesity traits in pigs. Obesity (Silver Spring). 2009 Dec 4. [Epub ahead of print].

Mote, B.E., J. W. Mabry, K .J. Stalder, and M. F. Rothschild. 2008. Current commercial sows: reproduction, culling, and mortality. Professional Animal Scientist (in press)

Schwab, C.R., B. E. Mote, Z. Du, R. Amoako, T. J. Baas, and M. F. Rothschild. 2008. An evaluation of four candidate genes for use in selection programs aimed at increased intramuscular fat in Duroc swine. J. Animal Breed and Genet. (accepted)

Doeschl-Wilson, A.B., I. Kyriazakis, A. Vincent, M. F. Rothschild, E. Thacker, and L. Galina-Pantoja. 2009. Clinical and pathological responses of pigs from two genetically diverse commercial lines to porcine respiratory and reproductive syndrome virus infection. J. Anim. Sci. (accepted).

Mote, B.E. K. J. Stalder, and M. F. Rothschild. 2008. Identification of genetic markers for sow productive life in commercial sows. J. Anim. Science (submitted)

Gorbach, D.M., Z-L. Hu, Z-Q. Du, M. F. Rothschild. 2009. SNP discovery in Litopenaeus vannamei with a new computational pipeline. A. Genet., 2008 Sep 26. [Epub ahead of print].

Alexander, L., S. Lonergan, M. F. Rothschild and C. Stahl. 2008. Response to dietary phosphorus deficiency is affected by genetic background in growing pigs. J. Ani. Sci (in press)

Wilke, V.L., S. Zhang, R. B. Evans, M. G. Conzemius, and M. F. Rothschild. 2009. Chromosomal regions associated with cranial cruciate ligament rupture in a population of Newfoundland dogs. Am. J. Vet. Res. (in press).

Zhao, X., Z.-Q. Du, N.Vukasinovic, F. Rodriguez, A.C. Clutter, and M. F. Rothschild. 2009. Bological candidate gene analyses identify that HOXA10 and MMP2 are associated with scrotal hernias in pigs. Am. J. Vet Res. (accepted).

Fan, B., S. K. Onteru, B. Mote, T. Serenius, K. J. Stalder, and M. F. Rothschild. 2009. Large-scale association study for structural soundness and leg locomotion traits in the pig. Genet. Sel. Evol. (accepted).

Fan, B., S.K. Onteru, G.S. Pastow, and M. F. Rothschild. 2009. Detailed characterization of the porcine MC4R gene in relation to fatness and growth. Anim. Genet. (accepted).

Guo,Y.M., H.S. Ai, J. Ren, G.J. Wang, Y. Wen, H.R. Mao, L.T. Lan, J.W. Ma, B. Brenig, M. F. Rothschild, C.S. Haley, and L.S. Huang. 2009. A whole genome scan for quantitative trait loci for leg weakness and its related traits in a large F2 intercross population between White Duroc and Erhualian. J. Anim. Sci. (accepted)


Other Links
Dr. Rothschild's CV
Cotswold Fellowship
Rothschild Lab Group