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Iowa State University

Iowa State University
Picture of Richard M.Robson
Richard M. Robson
Professor of Animal Science
Professor of Biochemistry, Biophysics & Molecular Biology
Iowa State University
3110 Molecular Biology Building
Ames, IA 50011-3260
Phone: 515-294-5036
Fax:     515-294-0453
Email: rmrobson@iastate.edu

Education
Iowa State University, Animal Science BS: 1964
Iowa State University, Biochemistry MS: 1966
Iowa State University, Biochemistry PhD: 1969

Awards
2004 ASAS Fellow
2002 ISU Alumni Association Faculty Citation
1998 ISU Foundation Award for Outstanding Achievement in Research
1997 ASAS Animal Growth & Development Research Award

Instruction
Dr. Robson teaches physiological chemistry (BBMB 420), molecular biology of muscle (AnS or BBMB 670), and seminar in muscle biology (AnS 685).

Research
Dr. Robson's area of research is biochemistry, molecular biology, and the structure and function of contractile and cytoskeletal proteins in muscle cells, with emphasis on critical proteins integrating and linking the contractile elements to each other and to other key cellular components. For more details on Dr. Robson's research, please see his Web page under the faculty listing for Biochemistry, Biophysics, and Molecular Biology.

Professional Affiliations
American Heart Association
American Meat Science Association
American Society of Animal Science
American Society for Biochemistry and Molecular Biology
American Society for Cell Biology
Institute of Food Technologists
Muscle Biology, section leader

Selected Publications
Complete list of Dr. Robson's publications

Graves, D. J., T. W. Huiatt, H. Zhou, H.-Y. Huang, S. W. Sernett, R. M. Robson and K. K. McMahon. 1997. Regulatory role of arginine-specific mono(ADP-ribosyl)transferase in muscle cells. Adv. Exp. Med. Biol. 419:305-313.

Hemken, P. M., R. M. Bellin, S. W. Sernett, B. Becker, T. W. Huiatt and R. M. Robson. 1997. Molecular characteristics of the novel intermediate filament protein paranemin. J. Biol. Chem. 272:32489-32499.

Ho, C.-Y., M. H. Stromer, G. Rouse and R. M. Robson. 1997. Effects of electrical stimulation and postmortem storage on changes in titin, nebulin, desmin, troponin-T, and muscle ultrastructure in Bos indicus crossbred cattle. J. Anim. Sci. 75:366-376.

Bilak, S. R., S. W. Sernett, M. M. Bilak, R. M. Bellin, M. H. Stromer, T. W. Huiatt and R. M. Robson. 1998. Properties of the novel intermediate filament protein synemin and its identification in mammalian muscle. Arch. Biochem. Biophys. 355:63-76.

Bellin, R. M., S. W. Sernett, B. Becker, W. Ip, T. W. Huiatt and R. M. Robson. 1999. Molecular characteristics and interactions of the intermediate filament protein synemin: Interactions with alpha-actinin may anchor synemin-containing heterofilaments. J. Biol. Chem. 274:29493-29499.

Schmidt, J. M., J. Zhang, H.-S. Lee, M. H. Stromer and R. M. Robson. 1999. Interaction of talin with actin: Sensitive modulation of filament crosslinking activity. Arch. Biochem. Biophys. 366:139-150.

Yuan, J., T. W. Huiatt, C. X. Liao, R. M. Robson and D. J. Graves. 1999. The effects of mono-ADP-ribosylation on desmin assembly-disassembly: Determination of the chemical features of bound ADP-ribose that prevent desmin filament formation. Arch. Biochem. Biophys. 363:314-322.

Carlsson, L., Z. L. Li, D. Paulin, M. G. Price, J. Breckler, R. M. Robson, G. Wiche and L.-E. Thornell. 2000. Differences in the distribution of synemin, paranemin and plectin in skeletal muscles of wild type and desmin knock-out mice. Histochem. Cell Biol. 114:39-47.

Sultana, S., S. W. Sernett, R. M. Bellin, R. M. Robson and O. Skalli. 2000. Intermediate filament protein synemin is transiently expressed in a subset of astrocytes during development. Glia 30:143-153.

Bellin, R. M., T. W. Huiatt, D. R. Critchley and R. M. Robson. 2001. Synemin may function to directly link muscle cell intermediate filaments to both myofibrillar Z-lines and costameres. J. Biol. Chem. 276:32330-32337.

Lee, H.-S., R. M. Bellin and R. M. Robson. 2001. Talin. In: Wiley Encyclopedia of Molecular Medicine, Vol. 5, John Wiley & Sons, Inc., New York, p..

Schweitzer, S. C., M. W. Klymkowsky, R. M. Bellin, R. M. Robson, Y. Capetanaki and R. M. Evans. 2001. Paranemin and the organization of desmin filament networks. J. Cell Sci. 114:1079-1089.

Carlsson, L., C. Fischer, G. Sjoberg, R. M. Robson, T. Segersen and L.-E. Thornell. 2002. Cytoskeletal derangements in hereditary myopathy with desmin L345P mutation. Acta Neuropathol. 104:493-504.

Lee, H.-S., R. M. Bellin, D. L. Walker, B. Patel, P. Powers, H. Liu, B. Garcia-Alvarez, J. M. de Pereda, R. C. Liddington, N. Volkmann, D. Hanein, D. R. Critchley and R. M. Robson. 2004. Characterization of an actin-binding site within the talin FERM domain. J. Mol. Biol. 343:771-784.

Jing, R., G. Pizzolato, R. M. Robson, G. Gabbiani and O. Skalli. 2005. Intermediate filament protein synemin is present in human reactive and malignant astrocytes and associates with ruffled membranes in astrocytoma cells. Glia 50:107-120.

Bhosle, R. C., D. E. Michele, K. P. Campbell, Z. Li and R. M. Robson. 2006. Interactions of intermediate filament protein synemin with dystrophin and utrophin. Biochem. Biophys. Res. Commun. 346:768-777.

Uyama, N., L. Zhao, E. Van Rossen, Y. Hirako, H. Reynaert, D. H. Adams, Z. Xue, Z. Li, R. Robson, M. Pekny and A. Geerts. 2006. Hepatic stellate cells express synemin, a protein bridging intermediate filaments to focal adhesions. Gut 55:1276-1289.

Sun, N., D. R. Critchley, D. Paulin, Z. Li and R. M. Robson. 2008. Human alpha-synemin interacts directly with vinculin and metavinculin. Biochem. J. 409:657-667.

Sun, N., D. R. Critchley, D. Paulin, Z. Li and R. M. Robson. 2008. Identification of a repeated domain within mammalian alpha-synemin that interacts directly with talin. Exp. Cell Res. 314:1839-1849.